tcga rna-seq normalized data Search Results


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Broad Institute Inc tcga level 3 pca rnaseq data
a Expression of mRNA encoding Hsp90 gene family members obtained from <t>TCGA</t> RNAseq data. Expression of mRNA encoding HSP90AA1, HSP90AB1 (Hsp90α/β), HSP90B1 (Grp94), and TRAP1 (TRAP1) in cancer and normal tissues from 52 patients with prostate cancer; ** p < 0.005, **** p < 0.0001. b Correlation between HSP90AA1 and TRAP1 (left), HSP90AB1 and TRAP1 (middle), and HSP90B1 and TRAP1 (right) expression in the TCGA RNAseq database. c Expression of Hsp90 paralogs in human prostate cancer specimens. The boundary between the normal (N) and tumor (T) regions is indicated. Tumor specimens were analyzed by immunofluorescence staining with anti-TRAP1, anti-Hsp90, and anti-Grp94 antibodies, and protein expression in single cells was analyzed by confocal microscopy. Scale bar, 1 mm. d Expression of TRAP1 vs. Hsp90 (left) and TRAP1 vs. Grp94 (right). Tumor specimens were analyzed as in c . Data from 87 cells are presented in scatter plots. Pearson correlation coefficient ( r ) and p values are indicated.
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MedCalc Software Ltd normalized rna-seq data tcga v2
a Expression of mRNA encoding Hsp90 gene family members obtained from <t>TCGA</t> RNAseq data. Expression of mRNA encoding HSP90AA1, HSP90AB1 (Hsp90α/β), HSP90B1 (Grp94), and TRAP1 (TRAP1) in cancer and normal tissues from 52 patients with prostate cancer; ** p < 0.005, **** p < 0.0001. b Correlation between HSP90AA1 and TRAP1 (left), HSP90AB1 and TRAP1 (middle), and HSP90B1 and TRAP1 (right) expression in the TCGA RNAseq database. c Expression of Hsp90 paralogs in human prostate cancer specimens. The boundary between the normal (N) and tumor (T) regions is indicated. Tumor specimens were analyzed by immunofluorescence staining with anti-TRAP1, anti-Hsp90, and anti-Grp94 antibodies, and protein expression in single cells was analyzed by confocal microscopy. Scale bar, 1 mm. d Expression of TRAP1 vs. Hsp90 (left) and TRAP1 vs. Grp94 (right). Tumor specimens were analyzed as in c . Data from 87 cells are presented in scatter plots. Pearson correlation coefficient ( r ) and p values are indicated.
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Broad Institute Inc bulk rna-seq and clinical data of tcga skcm
a Expression of mRNA encoding Hsp90 gene family members obtained from <t>TCGA</t> RNAseq data. Expression of mRNA encoding HSP90AA1, HSP90AB1 (Hsp90α/β), HSP90B1 (Grp94), and TRAP1 (TRAP1) in cancer and normal tissues from 52 patients with prostate cancer; ** p < 0.005, **** p < 0.0001. b Correlation between HSP90AA1 and TRAP1 (left), HSP90AB1 and TRAP1 (middle), and HSP90B1 and TRAP1 (right) expression in the TCGA RNAseq database. c Expression of Hsp90 paralogs in human prostate cancer specimens. The boundary between the normal (N) and tumor (T) regions is indicated. Tumor specimens were analyzed by immunofluorescence staining with anti-TRAP1, anti-Hsp90, and anti-Grp94 antibodies, and protein expression in single cells was analyzed by confocal microscopy. Scale bar, 1 mm. d Expression of TRAP1 vs. Hsp90 (left) and TRAP1 vs. Grp94 (right). Tumor specimens were analyzed as in c . Data from 87 cells are presented in scatter plots. Pearson correlation coefficient ( r ) and p values are indicated.
Bulk Rna Seq And Clinical Data Of Tcga Skcm, supplied by Broad Institute Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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a Expression of mRNA encoding Hsp90 gene family members obtained from TCGA RNAseq data. Expression of mRNA encoding HSP90AA1, HSP90AB1 (Hsp90α/β), HSP90B1 (Grp94), and TRAP1 (TRAP1) in cancer and normal tissues from 52 patients with prostate cancer; ** p < 0.005, **** p < 0.0001. b Correlation between HSP90AA1 and TRAP1 (left), HSP90AB1 and TRAP1 (middle), and HSP90B1 and TRAP1 (right) expression in the TCGA RNAseq database. c Expression of Hsp90 paralogs in human prostate cancer specimens. The boundary between the normal (N) and tumor (T) regions is indicated. Tumor specimens were analyzed by immunofluorescence staining with anti-TRAP1, anti-Hsp90, and anti-Grp94 antibodies, and protein expression in single cells was analyzed by confocal microscopy. Scale bar, 1 mm. d Expression of TRAP1 vs. Hsp90 (left) and TRAP1 vs. Grp94 (right). Tumor specimens were analyzed as in c . Data from 87 cells are presented in scatter plots. Pearson correlation coefficient ( r ) and p values are indicated.

Journal: Experimental & Molecular Medicine

Article Title: Unleashing the full potential of Hsp90 inhibitors as cancer therapeutics through simultaneous inactivation of Hsp90, Grp94, and TRAP1

doi: 10.1038/s12276-019-0360-x

Figure Lengend Snippet: a Expression of mRNA encoding Hsp90 gene family members obtained from TCGA RNAseq data. Expression of mRNA encoding HSP90AA1, HSP90AB1 (Hsp90α/β), HSP90B1 (Grp94), and TRAP1 (TRAP1) in cancer and normal tissues from 52 patients with prostate cancer; ** p < 0.005, **** p < 0.0001. b Correlation between HSP90AA1 and TRAP1 (left), HSP90AB1 and TRAP1 (middle), and HSP90B1 and TRAP1 (right) expression in the TCGA RNAseq database. c Expression of Hsp90 paralogs in human prostate cancer specimens. The boundary between the normal (N) and tumor (T) regions is indicated. Tumor specimens were analyzed by immunofluorescence staining with anti-TRAP1, anti-Hsp90, and anti-Grp94 antibodies, and protein expression in single cells was analyzed by confocal microscopy. Scale bar, 1 mm. d Expression of TRAP1 vs. Hsp90 (left) and TRAP1 vs. Grp94 (right). Tumor specimens were analyzed as in c . Data from 87 cells are presented in scatter plots. Pearson correlation coefficient ( r ) and p values are indicated.

Article Snippet: The Cancer Genome Atlas (TCGA) level 3 PCa RNAseq data were downloaded from the Broad Institute GDAC FireBrowse ( http://firebrowse.org , data version: 2016_01_28).

Techniques: Expressing, Immunofluorescence, Staining, Confocal Microscopy